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​​​​Which of the following sequence of events occurs during formation of egg-white gel?

Assume: $\mathrm{P}_{\mathrm{N}}$: Native protein; $\mathrm{P}_{\mathrm{D}}$: Denatured protein;
$\mathrm{P}_{\mathrm{A}}$: Aggregated protein; $\mathrm{P}_{\mathrm{G}}$: Protein gel
$\rightarrow$ forward reaction; $\leftrightarrow:$ reversible reaction; $\Delta$: heating; $\nabla$: cooling

  1. $\mathrm{P}_{\mathrm{N}} \stackrel{\Delta}{\leftrightarrow} \mathrm{P}_{\mathrm{D}} \stackrel{\nabla}{\leftrightarrow} \mathrm{P}_{\mathrm{A}} \stackrel{\nabla}{\leftrightarrow} \mathrm{P}_{\mathrm{G}}$
  2. $\mathrm{P}_{\mathrm{N}} \stackrel{\Delta}{\leftrightarrow} \mathrm{P}_{\mathrm{D}} \xrightarrow{\Delta} \mathrm{P}_{\mathrm{A}} \stackrel{\Delta}{\rightarrow} \mathrm{P}_{\mathrm{G}}$
  3. $\mathrm{P}_{\mathrm{N}} \stackrel{\Delta}{\leftrightarrow} \mathrm{P}_{\mathrm{D}} \stackrel{\nabla}{\rightarrow} \mathrm{P}_{\mathrm{G}}$
  4. $\mathrm{P}_{\mathrm{N}} \stackrel{\Delta}{\leftrightarrow} \mathrm{P}_{\mathrm{A}} \xrightarrow{\Delta} \mathrm{P}_{\mathrm{G}}$

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